Karin Rallmann CV

CURRICULUM VITAE

1 PERSONAL DATA

First Name: KARIN

Last Name: RALLMANN (former MÕTTUS)

Date of birth: Feb, 17, 1978

Citizen: Estonia

Address: Tartu county, Kambja, Lemmatsi, Ute 1a (postal code 61704)

Telephone (incl county code) +372 52 871 81

E-mail: rallmannkarin@gmail.com

Matrial status: married, two child (born 28.12.2003 and 23.12. 2009)

2 EDUCATION

2012 – 2018 Doctoral study, Amyotrophic lateral sclerosis (ALS) in Estonia: epidemiological, clinical and molecular study, University of Tartu, (sup) Pille Taba; Jonas Berquist (University of Uppsala)

2006 – 2012   Residency in neurology, University of Tartu2000 – 2006 Faculty of Medicine of the University of Tartu

(Master`s degree in medical specialty)

1997 – 2000 Faculty of Physical Education, University of Tartu,

(Bachelor’s degree in physiotherapy)

1996 – 1998 – Heino Eller Music College (department of choral conducting and school music)

1987 – 1992 – Antsla Children Music School

1993 – 1996 – Varstu High School

1985 – 1993 – Mõniste Primary School

3 MEDICAL LICENCE

D06704, issued in 2006

4 TRAINING and CONFERENCES

• IMCAS World Congress 2024, Paris, France, Feb, 1-3, 2024
• Sunekos trainings of the New ECM Regeneration System for Dermal

Biogenesis, Tallinn, Estonia, Jan, 24, 2024

• Merz Aesthetics hands on Training for Botulinum Toxin, Tartu, Estonia, Jan, 13,

2024

• Aesthetic medicine conference – from curves to cutting, EAP 7 points, Tallinn,

Estonia, Nov, 16, 2023

• Webinar MINT Lift Summit, Oct, 21, 2023, US
• Dissecting Aesthetics Webinar Series, Your Anatomical Roadmap to Treating

the Under Eyes, Oct, 4, 2023

• Dissecting Aesthetics Webinar Series, Your Anatomical Roadmap to Treating

the Pyriform, Oct, 18, 2023

• Injection Techniques Workshop by Dr Zafer Atakan, Tallinn, Estonia, Oct, 14,

2023

• Webinar Prevention and Management of Complications, Aesthetic Deep Dives,

Ipsen, Sept, 20, 2023

• Doublo-Gold Treatment Training Certification (High Intensity Focused

Ultrasound Lifting) a renowned World Class Product of Korea, Aug, 31, 2023

• Webinar Combined Techniques Medical and Surgical Approaches, Aesthetic

Deep, Dives, Ipsen, May, 17, 2023

• Merz Aesthetics hands on training for Radiesse and Belotero, Tallinn, Estonia,

March, 17-18, 2023

• EXPERT Ultrasound and anatomy workshop- Neck, Valencia, Spain, March, 3-

4, 2023

• Plasmolifting PRP Technology in Aesthetic Medicine and Trichology, Tartu,

Estonia, Dec, 17, 2022

• Merz Aesthetics hands on training for Radiesse and Botulinumtoxin, Tallinn,

Estonia, Dec, 3, 2022

• Merz Aesthetics hands on training for Radiesse and Belotero, Tallinn, Estonia,

Oct, 1, 2022

• Use of onabotulinum toxin A in the treatment of chronic migraine, Tartu,

Estonia, Sept 23, 2022

• Ipsen Aesthetic Academy, The AboFace Education Program, March, 26, 2022
• Ipsen Aesthetic Academy, The AboFace Education Program, Dec, 4, 2021
• The impact of motor relearning techniques on BoNT-A treatment in Dystonia

complex cases, advance course, Milan, Italy, April 12-13, 2018

• TOXINS 2015: Basic Science and Clinical Aspects of Botulinum and Other

Neurotoxins, Lisbon, Portugal, Jan, 14-17, 2015

• Cervical Dystonia (CD): the Col-Cap-Concept and individualized treatment,

Wiesbaden, Germany, Nov, 21-22, 2013

5 PREVIOUS EXPERIENCE WITH CLINICAL TRIALS

• 2018 – 2020 A randomised-controlled trial of thrombolytic treatment with tenecteplase for acute ischaemic stroke upon awakening.

TWIST, investigator

• 28.11.2018 – 31.12.2020 PREvention of Complications to Improve OUtcome in elderly patients with acute Stroke. A randomised, open, phase III, clinical trial with blinded outcome assessment. PRECIOUS, investigator

• 2020 – 2022 A Randomized, Double-Blindo Placebo-Controlled, Phase 2

Study to Assess Efficacyo Long Term SafeŅ and Tolerabilify of RT00l in Subjects with Amyotrophic Lateral Sclerosis

6 EPMLOYMENT2024, April 1, Edelli Skin and Beauty Clinic, Tartu, neurologist and doctor of aesthetic

medicine

2022 – 2024 Medita Clinic, Tartu, neurologist and doctor of aesthetic medicine

2022 – 2024, March, 31 – Pro-Age Clinic, Tartu, neurologist and doctor of aesthetic medicine

2012 – …    Tartu University Hospital, Department of Neurology, Neurologist01.09. 2006 – Tartu University Clinic Foundation Neurologist, resident doctor in neurology

30.07. 2003 – 31.09. 2006 – Tartu University Hospital, Department of Cardiovascular and

Thoracic Surgery, assistant nurse

01.06. 2001 – 30.07. 2003 Tartu University Clinic, Department of Cardiovascular and

Thoracic Surgery, nurse

7 ORGANIZATIONAL ACTIVITY

2024 Member of the Society of Aesthetic Non-Surgical Medicine

2022 Member of the Estonian Society of Aesthetic Medicine Doctors

2008 – Member of the Estonian Society of Movement Disorders (on the board, secretary)

2008– Member of the Society of Neurologists and Neurosurgeons named after Ludvig Puusepp

Member of the Stroke Working Group

2006 – Member of Tartu Doctors’ Association

8 LANGUAGES

Estonian, English, Russian

9 HOBBIES

Music, art, traveling, hiking

10 PUBLICATION

A randomized, double-blind, placebo-controlled phase 2 study to assess safety, tolerability, and efficacy of RT001 in patients with amyotrophic lateral sclerosis

• Daphne N Weemering¹, Mark Midei ², Peter Milner ², Vidhya Gopalakrishnan ²Anil Kumar ², Andrew J Dannenberg ³, Tommy M Bunte ¹, Juliette Foucher ^4 5, Caroline Ingre ^4 5, Viktorija Ķēniņa ^6 7, Karin Rallmann ⁸, Leonard H van den Berg ¹, Ruben P A van Eijk ^1 9, Clinical Trial, Eur J Neurol, 2023 Dec;30(12):3722-3731. doi: 10.1111/ene.16020.
• Skorvanek M, Martinez-Martin P, Kovacs N, Zezula I, Rodriguez-Violante M, Corvol JC, Taba P, Seppi K, Levin O, Schrag A, Aviles-Olmos I, Alvarez-Sanchez M, Arakaki T, Aschermann Z, Benchetrit E, Benoit C, Bergareche-Yarza A, Cervantes-Arriaga A, Chade A, Cormier F, Datieva V, Gallagher DA, Garretto N, Gdovinova Z, Gershanik O, Grofik M, Han V, Kadastik-Eerme L, Kurtis MM, Mangone G, Martinez-Castrillo JC, Mendoza-Rodriguez A, Minar M, Moore HP, Muldmaa M, Mueller C, Pinter B, Poewe W, Rallmann K, Reiter E, Rodriguez-Blazquez C, Singer C, Valkovic P, Goetz CG, Stebbins GT(2018). Relationship between the MDS-UPDRS and Quality of Life: A large multicenter study of 3206 patients. Parkinsonism & Related Disorders, 52, 83−89. DOI: 10.1016/j.parkreldis.2018.03.027.

• Skorvanek M,Martinez-Martin P, Kovacs N, Rodriguez-Violante M, Corvol JP, Taba P, Seppi K, Levin O, Schrag A, Foltynie T, Alvarez-Sanchez M, Arakaki T, Aschermann Z , Aviles-Olmos I, Benchetrit E, Benoit C, Bergareche-Yarza A, Cervantes-Arriaga A, Chade A, Cormier F, Datieva V, Gallagher D, Garretto N, Gdovinova Z, Gershanik O, Grofik M, Han V, Huang J, Kadastik-Eerme L, Kurtis MM, Mangone G, Martinez-Castrillo JC, Mendoza-Rodriguez A, Minar A, Moore HP, Muldmaa M, Mueller C, Pinter B, Poewe W, Rallmann K, Reiter E, Rodriguez-Blazquez C, Singer C, Tilley BC, Valkovic P, Goetz CG, Stebbins GT. (2017). Differences in MDS-UPDRS scores based on Hoehn & Yahr stage and disease duration. Movement Disorders Clinical Practice, 4, 536−544. DOI: 10.1002/mdc3.12476.

• Skorvanek M, Martinez-Martin P, Kovacs N, Zezula I, Rodriguez-Violante M, Corvol JP, Taba P, Seppi K, Levin O, Schrag A, Foltynie T, Alvarez-Sanchez M, Arakaki T, Aschermann Z , Aviles-Olmos I, Benchetrit E, Benoit C, Bergareche-Yarza A, Cervantes-Arriaga A, Chade A, Cormier F, Datieva V, Gallagher D, Garretto N, Gdovinova Z, Gershanik O, Grofik M, Han V, Huang J, Kadastik-Eerme L, Kurtis MM, Mangone G, Martinez-Castrillo JC, Mendoza-Rodriguez A, Minar A, Moore HP, Muldmaa M, Mueller C, Pinter B, Poewe W, Rallmann K, Reiter E, Rodriguez-Blazquez C, Singer C, Tilley BC, Valkovic P, Goetz CG, Stebbins GT. (2016). Relationship between the MDS-UPDRS and Quality of Life in Parkinson’s Disease: A Large International Multicenter Study of 3206 patients (the QUALPD study). Movement Disorders, 31 (Suppl 2), S163−S163.

• Skorvanek M, Martinez-Martin P, Kovacs N, Zezula I, Rodriguez-Violante M, Corvol JP, Taba P, Seppi K, Levin O, Schrag A, Foltynie T, Alvarez-Sanchez M, Arakaki T, Aschermann Z , Aviles-Olmos I, Benchetrit E, Benoit C, Bergareche-Yarza A, Cervantes-Arriaga A, Chade A, Cormier F, Datieva V, Gallagher D, Garretto N, Gdovinova Z, Gershanik O, Grofik M, Han V, Huang J, Kadastik-Eerme L, Kurtis MM, Mangone G, Martinez-Castrillo JC, Mendoza-Rodriguez A, Minar A, Moore HP, Muldmaa M, Mueller C, Pinter B, Poewe W, Rallmann K, Reiter E, Rodriguez-Blazquez C, Singer C, Tilley BC, Valkovic P, Goetz CG, Stebbins GT. (2016). Differences in MDS-UPDRS scores based on Hoehn and Yahr stage and disease duration: results of a large international multicentre study of 3206 patients (the QUALPD study). Movement Disorders, 31 (Suppl2), S513−S513.

• Rallmann K, Liik M, Taba P. (2016). Botulismitoksiini kliiniline kasutamine. Eesti Arst, 95 (3), 171−178.

• Muldmaa, M.; Põldsepp, S.; Kadastik-Eerme, L.; Rallmann, K.; Taba, P. (2013). Impulsive-compulsive behaviour in patients with Parkinson´s disease. Journal of Neurology, 260 (S1): 23rd Meeting of the European Neurological Society; Barcelona, Spain; 9.-12.06, 2012. Springer Heidelberg, S138−S139.

• Kadastik-Eerme, L.; Paju, T.; Rallmann, K.; Rosenthal, M.; Taba, P. (2013). Tervisega seotud elukvaliteet ja seda mõjutavad tegurid Parkinsoni tõve korral. Eesti Arst, 92, 45−45.

• Muldmaa, M.; Põldsepp, S.; Taba, P.; Rallmann, K.; Kadastik-Eerme, L. (2012). Impulsiiv-kompulsiivne häire Parkinsoni tõve haigetel. Eesti Arst, 91(Lisa 1), 43.

• Rallmann, K.; Kadastik-Eerme, L.; Rosenthal, M.; Taba, P. (2012). Pharmacotherapy of Parkinson’s disease in Estonia: strategies and complications. Movement Disorders, 27 (S1), S49.
• Rallmann, K.; Taba, P. (2009). Treatment of Parkinson’s disease in Estonia. European Journal of Neurology, 16, 571−572.

• Braschinsky, M., Vibo, R., Rallmann, K., Asser, A., Tomberg, T. (2007). Aju venoossete siinuste tromboos. Eesti Arst, 86 (12), 897−902.

• Pääsuke, M.; Ereline, J.; Gapeyeva, H.; Joost, K.; Mõttus, K.; Taba, P. (2004). Leg-extension strength and chair-rise performance in elderly women with Parkinson’s disease. Journal of Aging and Physical Activity, 12 (4), 511−524.

• Pääsuke, M.; Mõttus, K.; Ereline, J.; Gapeyeva, H.; Taba, P. (2002). Lower, limb performance in older female patients with Parkinson’s disease. Aging Clinical and Experimental Research, 14 (3), 185−191.

• Braschinsky M., Vibo R., Rallmann K., Asser A., Tomberg T. Aju venoossete siinuste tromboos. Eesti Arst 2007; 86 (12): 897–902

Karin Rallmann, MD March, 22; 2024